The recovery profiles
after anaesthesia with desflurane or sevoflurane combined with TCI Propofol and
TCI Remifentanil in morbidly obese patients.
Alisher Agzamov, A. M. Al Qattan, Mohammad Al
Khashti, Mohammad Behzad.
The Department of Anaesthesiology & ICU,
Al Sabah & Zain Hospitals, Kuwait City, KUWAIT..
This randomized prospective study with blinded
postanaesthesia care unit (PACU) observers compared the recovery profiles in
morbidly obese patients who received sevoflurane or desflurane for maintenance
of anaesthesia in combination with a Remifentanil target controlled infusion
(TCI).
420 morbidly obese patients (BMI > 40 - 75)
scheduled for laparoscopic gastric banding were included to receive AEP and
BIS-guided sevoflurane or desflurane anaesthesia with AEP & BIS-triggered
inhalation in combination with TCI Propofol & TCI Remifentanil. In the
PACU, the following recovery scores were investigated: Modified Aldrete score,
a modified Observers Assessment of Alertness/Sedation Scale (OAA/S), pain numerical
rating scale (NRS), oxygen saturation (SpO(2)) and postoperative nausea and
vomiting (PONV).
OAA/S and NRS pain scores showed a similar
evolution in both groups from the moment of PACU admission up to 30 minutes
after admission. In both groups, patients showed no serious hypoxemia during
PACU stay. Incidence of PONV was shorter lasting in the sevoflurane group
compared to the desflurane group.
No clinically relevant difference was found in
recovery in the PACU between morbidly obese patients anesthetized with
desflurane or sevoflurane. Both anesthetics gases: sevoflurane and desflurane
resulted in satisfactory recovery in morbidly obese patie
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